Detection and Treatment of Sarcopenia and Myosteatosis in Older African Americans
NCT02350465 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 136
Last updated 2023-06-02
Summary
The objectives of this study are to: 1) validate a rapid, portable, cost-effective method for screening myosteatosis and sarcopenia using diagnostic ultrasound, and 2) investigate a novel approach to progressive resistance exercise involving eccentric muscle actions that will counter the local effects of myosteatosis and sarcopenia in African Americans.
Conditions
Interventions
- BEHAVIORAL
-
Eccentric Exercise
Submaximal progressive resistance exercise (PRE) using eccentric muscle actions for the knee extensors/flexors will be performed for 10 repetitions, 3 to 4 sets, twice per week for 12 weeks.
- BEHAVIORAL
-
Concentric Exercise
Submaximal progressive resistance exercise (PRE) using concentric muscle actions for the knee extensors/flexors will be performed for 10 repetitions, 3 to 4 sets, twice per week for 12 weeks.
Sponsors & Collaborators
-
VA Office of Research and Development
lead FED
Principal Investigators
-
Michael Harris-Love, DSc MPT BS · Rocky Mountain Regional VA Medical Center, Aurora, CO
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2015-03-01
- Primary Completion
- 2022-08-31
- Completion
- 2023-09-01
Countries
- United States
Study Locations
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