MedTrace Logo

Role of MicroRNAs on Age and Contraction-induced Skeletal Muscle Growth

NCT02638454 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2025-07-20

No results posted yet for this study

Summary

Sarcopenia is a predictor of functional-limitation, leading to loss of independence, lowered quality of life, and ultimately death. The impaired ability of aged skeletal muscle to adapt to anabolic stimulation may be a factor that contributes to sarcopenia. This project will provide novel insights into the role of microRNA in the attenuation of aging skeletal muscle to changes in gene expression after anabolic stimulation.

Conditions

Interventions

PROCEDURE

Acute Resistance Exercise

1 bout of high-intensity resistance exercise at 80% of the individuals 1 repetition maximum

Sponsors & Collaborators

  • Tufts University

    lead OTHER

Principal Investigators

  • Donato A Rivas, PhD · Tufts University

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
SINGLE_GROUP

Eligibility

Min Age
20 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-08-31
Primary Completion
2019-01-31
Completion
2019-01-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02638454 on ClinicalTrials.gov