Study of Predictive Factors Related to Prognosis of Patients With Ischemic Stroke Due to Large-artery Atherosclerosis
NCT04847752 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1000
Last updated 2024-06-20
Summary
This is a single-center prospective cohort study of predictive factors related to prognosis of ischemic stroke due to large-artery atherosclerosis.
From March 1, 2021 to December 31, 2026, 1000 patients with ischemic stroke due to large-artery atherosclerosis who are admitted to the Department of Neurology or Neurosurgery, Tongji Hospital are going to be recruited. Detailed clinical data in emergency room and in-hospital will be obtained from the medical record reviews, and the National Institutes of Health Stroke Scale (NIHSS) and Modified Rankin Scale (mRS) score will be done by certified neurologists to assess the severity of the disease in acute stage and treatment outcome during the follow-up. All cases will undergo routine blood tests, brain magnetic resonance imaging (MRI) and cerebral vascular examination, such as TCD, CTA, HRMR or DSA. The investigators will analyze the in-hospital factors that could predict the outcome to provide more evidence-based suggestions in the treatment and prognosis of atherosclerotic ischemic cerebrovascular disease.
Conditions
- Ischemic Stroke
- Large-Artery Atherosclerosis (Embolus/Thrombosis)
Interventions
- PROCEDURE
-
carotid artery stenting
common treatments for carotid artery stenosis
- PROCEDURE
-
carotid endarterectomy
common treatments for carotid artery stenosis
- DRUG
-
the dosage and duration
- DRUG
-
Clopidogrel
the dosage and duration
- DRUG
-
Anticoagulant
the dosage and duration
- DRUG
-
Statin
the dosage and duration
- DRUG
-
PCSK9 inhibitor
the dosage and duration
Sponsors & Collaborators
-
Tongji Hospital
lead OTHER
Principal Investigators
-
Dai-Shi Tian, Dr. · Tongji Hospital
-
Chuan Qin, Dr. · Tongji Hospital
-
Jun Xiao, Dr. · Tongji Hospital
-
Ke Shang, Dr. · Tongji Hospital
Eligibility
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-03-01
- Primary Completion
- 2026-12-31
- Completion
- 2028-12-31
Countries
- China
Study Locations
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