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Large Artery Occlusion Treated in Extended Time With Mechanical Thrombectomy Trial

NCT05326932 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 382

Last updated 2026-03-06

No results posted yet for this study

Summary

A multi-center, prospective, randomized, open-label, adaptive group sequential designed, blinded endpoint assessment (PROBE) clinical trial of endovascular treatment among selected AIS

Conditions

  • Acute Ischemic Stroke

Interventions

PROCEDURE

Mechanical thrombectomy

Subjects in intervention group will receive MT as soon as possible. Investigators and clinicians should strive to reduce delays of pre-surgery procedure and follow the local standard guideline of MT during the operation and perioperative period. All CFDA approved devices are allowed in this trial. Angioplasty and stent placement can be performed at the discretion of the physicians. Base on site experience, the randomization-operation start period should be within 60 minutes.

Sponsors & Collaborators

  • Changhai Hospital

    collaborator OTHER

  • The George Institute for Global Health, China

    lead OTHER

Principal Investigators

  • Craig Anderson, PhD · The George Institute for Global Health, China

  • Jianmin Liu · Changhai Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-11-03
Primary Completion
2026-03-31
Completion
2028-03-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05326932 on ClinicalTrials.gov