Aspirin (acetylsalicylic acid) is a nonsteroidal anti-inflammatory drug used for pain, fever, inflammation, and antithrombotic prevention. It is widely available as an over-the-counter medicine in many jurisdictions and remains one of the most used medicines globally. It also has long-term preventive use in selected cardiovascular patients.
Research into Lynch syndrome is advancing cancer prevention through aspirin therapy, vaccine trials, and a major North American study examining why some patients develop cancer while others remain protected.
Daily aspirin use does not prevent bowel cancer in the general population within 5-15 years and carries immediate bleeding risks, according to a new Cochrane review. However, long-term low-dose aspirin is associated with lower colorectal cancer risk in IBD patients.
Lynch syndrome patients gain access to prevention vaccines in clinical trials, while immunotherapy advances depend on universal tumor testing for microsatellite instability. Cancer vaccines are moving from research to clinical reality.
New research identifies circulating tumor-reactive T cell characteristics and inflammatory biomarkers as predictive indicators for immune checkpoint inhibitor response in cancer patients, while the PD-L1 testing market is projected to reach $36.44 billion by 2032.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07779057 |
Comparison of High- Versus Low-Dose Aspirin for Pregnancy Outcomes in Women at High Risk of Preeclampsia |
RECRUITING | PHASE4 |
| NCT07746882 |
Study on Anti-Thrombotic Regimens for Secondary Prevention in Ischemic Stroke Patients With Possible Benefit From Anticoagulation Therapy |
NOT_YET_RECRUITING | PHASE3 |
| NCT07744191 |
A Clinical Trial of Antiplatelets in Psoriasis |
NOT_YET_RECRUITING | PHASE4 |
| NCT07720934 |
A Pilot Study to Investigate Platelet Reactivity in Patients With Elevated Lipoprotein(a) and Its Response to Antiplatelet Therapy |
NOT_YET_RECRUITING | NA |
| NCT07719894 |
Cilostazol and Aspirin for Cardiovascular Event Prevention in Patients With Type 2 Diabetes |
RECRUITING | PHASE4 |
| NCT07686770 |
Efficacy and Safety of Immunoglobulin Plus Firsekibart in Patients With Kawasaki Disease |
NOT_YET_RECRUITING | PHASE2/PHASE3 |
| NCT07677410 |
Aspirin Monotherapy Versus Sequential Warfarin-Aspirin Therapy After TAVR in Patients With Pure Aortic Regurgitation |
RECRUITING | NA |
| NCT07658807 |
Evaluating Bu Yang Huanwu Decoction For Early Diabetic Vascular Disease |
NOT_YET_RECRUITING | PHASE3 |
| NCT07652723 |
A Study to Learn About How Safe BAY3389934 is and How it Affects Blood Clotting When Given Alone or With Aspirin in Healthy Participants |
RECRUITING | PHASE1 |
| NCT07644234 |
Platelet Aggregation Function-Guided De-Escalation Antiplatelet Therapy in Patients With Acute Ischemic Stroke |
NOT_YET_RECRUITING | PHASE4 |
