Aspirin (acetylsalicylic acid) is a nonsteroidal anti-inflammatory drug used for pain, fever, inflammation, and antithrombotic prevention. It is widely available as an over-the-counter medicine in many jurisdictions and remains one of the most used medicines globally. It also has long-term preventive use in selected cardiovascular patients.
Research into Lynch syndrome is advancing cancer prevention through aspirin therapy, vaccine trials, and a major North American study examining why some patients develop cancer while others remain protected.
Daily aspirin use does not prevent bowel cancer in the general population within 5-15 years and carries immediate bleeding risks, according to a new Cochrane review. However, long-term low-dose aspirin is associated with lower colorectal cancer risk in IBD patients.
Lynch syndrome patients gain access to prevention vaccines in clinical trials, while immunotherapy advances depend on universal tumor testing for microsatellite instability. Cancer vaccines are moving from research to clinical reality.
New research identifies circulating tumor-reactive T cell characteristics and inflammatory biomarkers as predictive indicators for immune checkpoint inhibitor response in cancer patients, while the PD-L1 testing market is projected to reach $36.44 billion by 2032.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07597239 |
Thromboelastography With Platelet Mapping to Guide Antiplatelet Therapy After Lower Extremity Revascularization |
ACTIVE_NOT_RECRUITING | NA |
| NCT07572747 |
Aspirin Versus Clopidogrel in Chronic Coronary Syndrome in Arabian Gulf Countries |
NOT_YET_RECRUITING | PHASE3 |
| NCT07540416 |
Tenecteplase for Late-Window Stroke Guided by DWI-FLAIR Mismatch |
NOT_YET_RECRUITING | PHASE3 |
| NCT07525635 |
Aspirin Dosing in Pregnancy |
RECRUITING | EARLY_PHASE1 |
| NCT07431762 |
Comparison of Anti-Thrombotic Treatments Between Aspirin and Warfarin During Initial Six Months After Bioprpsthetic Heart Valve Replacement |
NOT_YET_RECRUITING | PHASE4 |
| NCT07373756 |
Randomized Controlled Study to Compare Efficacy of Aspirin 75mg and 150mg In the Prevention of Preeclampsia In High Risk Pregnant Women |
NOT_YET_RECRUITING | PHASE4 |
| NCT07361679 |
LDA and LMWH vs LDA Alone in High-risk Patients for Preeclampsia Prevention |
RECRUITING | PHASE4 |
| NCT07358416 |
Complications and Antiplatelet and Anticoagulant Therapy in Vascular Surgery. |
ACTIVE_NOT_RECRUITING | |
| NCT07338331 |
Comparative Effects of Aspirin and SGLT2 Inhibitors on Liver Enzymes, Lipid Profile, and FibroScan Findings in Non-Alcoholic Fatty Liver Disease |
COMPLETED | NA |
| NCT07180472 |
Prevention of Stroke Recurrence and Disease Progression in Cerebral Small Vessel Disease With Cilostazol |
NOT_YET_RECRUITING | PHASE4 |
