MedTrace Logo

Exercise Effects on Adipose Tissue Structure and Function

NCT04812314 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 46

Last updated 2025-06-29

No results posted yet for this study

Summary

Participants will be randomized into one of two different experimental groups: 1) Exercise group and 2) No exercise (control group). Subject participation in the study will involve a series of metabolic tests before and after participants undergo a 10% weight loss program (with or without exercise training depending on group randomization). After completing this weight loss portion of the study, participants will then be required to adhere to a high calorie diet program to regain half of the weight the participant lost - followed by the same series of metabolic tests.

Conditions

Interventions

BEHAVIORAL

Exercise

Participants will complete a moderate intensity continuous exercise 4 days/week.

BEHAVIORAL

No exercise

Participants will remain sedentary throughout the duration of the study.

Sponsors & Collaborators

Principal Investigators

  • Jeffrey F Horowitz, PhD · University of Michigan, School of Kinesiology

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-03-01
Primary Completion
2026-03-01
Completion
2030-03-01

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04812314 on ClinicalTrials.gov