Metabolic syndrome is a cluster of cardiometabolic risk factors including abdominal obesity, dyslipidemia, hypertension, and hyperglycemia that together increase risks of cardiovascular disease and type 2 diabetes.
GLP-1 receptor agonists are linked to a higher risk of smell and taste disturbances, while poison control calls involving semaglutide have soared since 2021. The drugs produce significant weight loss and are reshaping U.S. food demand, with roughly one in eight adults now taking them.
Updated pediatric hypertriglyceridemia guidance says triglyceride thresholds below 400 mg/dL mainly signal ASCVD risk, while levels above about 885 mg/dL raise pancreatitis risk. Lifestyle changes remain first-line treatment, and pediatric-specific evidence for drug therapy is still limited.
Obesity contributes to about 1 in every 4 infectious disease deaths in the United States and 1 in 10 globally, according to a major study. People with obesity face 70% higher risk of hospitalization or death from infections, with risk tripling at severe obesity levels.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07770282 |
Efficacy and Safety of Semaglutide Versus Placebo on Cardiometabolic Profile in Patients With Schizophrenia With Metabolic Syndrome |
NOT_YET_RECRUITING | PHASE3 |
| NCT07766928 |
Lipid and Glucose Response to Plant-based and Regular Burgers |
NOT_YET_RECRUITING | NA |
| NCT07763626 |
Gdue Plus a Hypocaloric Mediterranean Diet in Adults With MASLD |
COMPLETED | NA |
| NCT07759323 |
Polygonatum Sibiricum Reduces Visceral Fat in Obese Adults |
NOT_YET_RECRUITING | NA |
| NCT07758842 |
Lifestyle Modification for Erectile Dysfunction in Men With Metabolic Syndrome |
RECRUITING | NA |
| NCT07739602 |
Effects of Cornelian Cherry Supplementation in Patients With Metabolic Syndrome |
COMPLETED | NA |
| NCT07728669 |
Digital Dietary Intervention for Patients Receiving GLP-1 Receptor Agonist Therapy |
RECRUITING | NA |
| NCT07707778 |
Tirzepatide's Effects on Epigenetic Aging and Metabolic Restoration in Virally Suppressed People With HIV |
ENROLLING_BY_INVITATION | PHASE4 |
| NCT07703371 |
Kodo Millet Porridge and Its Effects on Gut Health and Metabolic Syndrome |
RECRUITING | NA |
| NCT07702695 |
A Mediterranean Diet-Based Culinary Intervention in Adults With Metabolic Syndrome |
NOT_YET_RECRUITING | NA |
