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Impact of Underlying Renal Disease and Immunosuppressive Regimen on Ovarian Reserve in Renal Patients

NCT04762615 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 153

Last updated 2021-02-21

No results posted yet for this study

Summary

Aging, renal pathology (eg SLE, ADPKD), X-ray exposition and pharmacological treatments, especially previous strong immunosuppression, may negatively influence the ovarian reserve in childbearing age women. Anti-Müllerian hormone (AMH) is regarded as biomarker for ovarian reserve.

Every female with renal disease regularly menstruating that met exclusion criteria could have participated. The aim was to assess ovarian reserve in female patients with normal menstrual cycle and kidney disease, including kidney transplant recipients.

Conditions

  • Anti-Mullerian Hormone Deficiency
  • Immunosuppression
  • Ovarian Reserve
  • X-rays; Effects

Interventions

DIAGNOSTIC_TEST

AMH level measurement

AMH level measurement using ELISA test from blood samples

Sponsors & Collaborators

  • Wroclaw Medical University

    lead OTHER

Principal Investigators

  • Julia Rasała, MD · Wroclaw Medical University

Eligibility

Min Age
18 Years
Max Age
44 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-06-01
Primary Completion
2019-11-10
Completion
2020-12-01

Countries

  • Poland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04762615 on ClinicalTrials.gov