Cardiovascular Risk Factors After Renal Transplantation in Children and Adults

NCT01008306 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2009-11-05

No results posted yet for this study

Summary

Renal transplantation of children started in Norway in 1970.Since the beginning, \>80% of renal transplants are provided from Living Donors(mainly parents), short pre-transplant dialysis time( median 4 months) and 50% of transplantations are performed before dialysis is needed.This gives good premises for graft survival and avoidance of detrimental effects of dialysis. However, renal transplanted children are subjected to an increased cardiovascular morbidity and mortality in adulthood due to consequences of chronic renal failure and immunosuppressive treatment.Cardiovascular death comprises 30-40% of death causes. In this cross-sectional study we evaluate cardiovascular risk factors in childhood- and also in young adults renal transplanted in childhood.

Focus is cardiorespiratory fitness using treadmill testing,24h BP measurements, anthropometrics including waist circumference,echocardiography,intima media thickness of carotids, glucose intolerance test.Participants are also requested to fill out physical activity recalls and Quality of life questionnaires.

Conditions

  • Exercise Capacity
  • Physical Activity
  • Hypertension
  • Overweight and Obesity
  • Metabolic Syndrome

Sponsors & Collaborators

  • Norwegian Red Cross

    collaborator OTHER
  • Oslo University Hospital

    lead OTHER

Eligibility

Min Age
2 Years
Max Age
38 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-06-30
Primary Completion
2010-06-30

Countries

  • Norway

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01008306 on ClinicalTrials.gov