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MRI in Renal Transplantation

NCT03705091 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2018-10-15

No results posted yet for this study

Summary

Renal transplantation is the optimal method of treatment for end stage kidney disease however median lifespan of a kidney transplant is around 15 years. Existing methods of measuring transplant function and structure from blood and urine markers are imperfect; renal biopsy is often performed but is invasive. Novel methods of investigating transplant function are therefore required and emerging renal MRI sequences including ASL and diffusion weighted imaging may yield helpful biomarkers. Investigators will recruit 20 patients in the first year after transplant and measure MRI biomarkers at three time points, with correlation to existing methods of measuring transplant function.

Conditions

  • End Stage Renal Disease
  • Renal Transplant Rejection
  • Kidney Transplant Failure and Rejection
  • Chronic Kidney Diseases

Interventions

DIAGNOSTIC_TEST

Magnetic resonance imaging

ASL and DWI MRI

Sponsors & Collaborators

  • NHS Greater Glasgow and Clyde

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-04-11
Primary Completion
2019-02-20
Completion
2019-03-20

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03705091 on ClinicalTrials.gov