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Alpha-Ketoglutarate and Abdominal Aortic Aneurysm Progression and Rupture

NCT04723888 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 300

Last updated 2021-02-21

No results posted yet for this study

Summary

The objective of this project is to define whether nutritional supplement (oral administration with alpha-ketoglutarate) capable of filling-up the citric acid cycle (anaplerotic therapy) can improve outcomes in patients with an abdominal aortic aneurysm of 39-49 mm in diameter on ultrasound imaging. Alpha-ketoglutarate is commonly used as a nutritional supplement specially by athletes to increase muscle strength. They can be mixed with formula or other foods. Subjects will be followed for up to 5 years.

Conditions

  • Patients With an Abdominal Aortic Aneurysm of 39-49 mm in Diameter

Interventions

DIETARY_SUPPLEMENT

alpha-ketoglutarate

alpha-ketoglutarate supplements

Sponsors & Collaborators

  • RenJi Hospital

    lead OTHER

Principal Investigators

  • Jun Pu · RenJi Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-02-01
Primary Completion
2026-02-01
Completion
2026-12-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04723888 on ClinicalTrials.gov