Treatment of Unruptured Intracranial Aneurysms in China

Summary

Un-ruptured intracranial aneurysm is a complex disease that seriously affects human life and health. At present, the treatment of intracranial aneurysm is divided into interventional treatment and craniotomy clipping, the two treatment methods are different in the intervention effect of aneurysm, for example, the complications of interventional therapy are lower than craniotomy clipping, but the long-term patency rate is lower than craniotomy clipping, and there is no standard of treatment in different parts of aneurysm in our country, the choice of intervention measures of un-ruptured aneurysm is different in different clinical centers; on the other hand, there are serious problems in the treatment of aneurysms, because without the relevant guidelines of diagnosis and treatment of intracranial aneurysms, different clinical centers will cause excessive treatment of un-ruptured aneurysms, not only bring unreasonable utilization of medical resources, but also cause the subject's life and property to be threatened.

The patients with un-ruptured intracranial aneurysm(estimated sample number over 1500) were included in prospective cohort study, after clipping and intervention operation, setting fixed time for postoperative follow-up, the clinical data and image data were recorded, the safety, efficacy and economic benefits of interventional treatment and craniotomy clipping were compared, providing strategies for the standardized treatment of un-ruptured intracranial aneurysms.

Conditions

• Intracranial Aneurysm
• Stent Embolisation
• Craniotomy
• Coil-assissted Embolisation
• Covered Stent
• Woven EndoBridge

Sponsors & Collaborators

• Xuanwu Hospital, Beijing

  collaborator OTHER

• Beijing Tiantan Hospital

  collaborator OTHER

• Guangdong Provincial People's Hospital

  collaborator OTHER

• First Affiliated Hospital of Chongqing Medical University

  collaborator OTHER

• The Affiliated Hospital Of Southwest Medical University

  collaborator OTHER

• West China Hospital

  collaborator OTHER

• Shenzhen Second People's Hospital

  collaborator OTHER

• Guangdong 999 Brain Hospital

  collaborator OTHER

• Shantou Central Hospital

  collaborator OTHER

• ZhuHai Hospital

  collaborator OTHER

• Zhongshan Hospital Of Traditional Chinese Medicine

  collaborator OTHER

• Third Affiliated Hospital, Sun Yat-Sen University

  collaborator OTHER

• Eighth Affiliated Hospital, Sun Yat-sen University

  collaborator OTHER

• Zhujiang Hospital

  lead OTHER

Principal Investigators

• Chuanzhi Duan, Ph.D. · Department of Neurosurgery, Southern Medical University, Zhujiang Hospital

Eligibility

Min Age

14 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2016-01-01

Primary Completion

2022-12-30

Completion

2022-12-30

Countries

• China

Study Locations