The Epidemiology of Aortic Diameter in China

NCT00820378 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 2000

Last updated 2009-01-14

No results posted yet for this study

Summary

Aortic aneurysms are the major disease processes affecting the aorta and becoming a relatively common cause of death because of rupture or dissection. The most common location for aneurysms is the infrarenal abdominal aorta, followed by the ascending thoracic aorta. Unlike coronary heart disease, the incidence of abdominal aortic aneurysm (AAA) in the United States and Europe has been increasing, and this increase may not be due to higher levels of screening for this condition alone. Aortic diameter is central to the diagnosis of aortic aneurysm. Furthermore, it was demonstrated that non-AAA patients with an enlarged diameter of the infrarenal aortic diameter are also at high risk for all-cause mortality. And aortic root dimension was associated with several coronary artery disease (CHD) risk factors and measures of subclinical disease and was predictive of incident congestive heart failure (CHF), stroke, cardiovascular disease (CVD) mortality, and all-cause mortality, but not of incident MI. Up to now, there are limited studies on the epidemiology of aortic diameter, especially in Chinese population.

Conditions

Interventions

OTHER

No special interventioin

Comprehensive transthoracic M-mode, 2-dimensional, and Doppler echocardiographic studies will be performed using commercially available equipment. The aortic dimensions were assessed at end-diastole at the different levels:

Sponsors & Collaborators

  • Taizhou Hospital

    collaborator OTHER
  • Zhejiang University

    lead OTHER

Principal Investigators

  • Jian-an Wang · Second Affiliated Hospital, School of Medicine, Zhejiang University

  • Li-jiang Tang · Taizhou Hospital, Wenzhou Medical College

  • Xiao-feng Chen · Second Affiliated Hospital, School of Medicine, Zhejiang University

  • Zhao-xia Pu · Second Affiliated Hospital, School of Medicine, Zhejiang University

  • Xian-fang Lin · Taizhou Hospital, Wenzhou Medical College

Eligibility

Min Age
40 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-01-31
Primary Completion
2010-12-31
Completion
2015-12-31

Countries

  • China

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00820378 on ClinicalTrials.gov