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Predicting Aneurysm Growth and Rupture With Longitudinal Biomarkers

NCT03320408 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 790

Last updated 2023-08-22

No results posted yet for this study

Summary

First aim: PARIS study

The main aim of the current study is to determine the association between abdominal aortic aneurysm (AAA) progression and the evolution of proteases and cytokines levels.To achieve this aim, we will prospectively collect blood, aortic tissue, patient data, and imaging data. Aortic tissue will only be obtained when patients undergo conventional open repair. The other biomaterials will be collected during regular patient follow-up visits, with a maximum frequency of once per year.

Second aim: Pearl AAA biobank

For future research purposes, a new biobanking infrastructure will be created to collect and store additional blood and urine samples in a biobank. This biobank will be embedded within the infrastructure of the 'Parelsnoer Institute' (PSI) and will be called Pearl AAA. The Pearl AAA will be established in the extension of the PARIS study

Conditions

  • Abdominal Aortic Aneurysm
  • Abdominal Aortic Aneurysm, Ruptured

Sponsors & Collaborators

  • Ron Balm

    lead OTHER

Principal Investigators

  • Ron Balm, MD PhD · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-10-04
Primary Completion
2023-08-04
Completion
2023-08-04

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03320408 on ClinicalTrials.gov