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Dinner Time 2: Effect of Delayed Eating or Sleeping on Metabolism

NCT04671797 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 41

Last updated 2026-02-04

No results posted yet for this study

Summary

This study examines the acute impact of eating an "early" versus "late" dinner. "Early" and "late" will be customized to individuals based on the individuals' own circadian rhythms. Healthy adults will have the adults' circadian rhythm assessed by measuring the adults' dim light melatonin onset (DLMO). Based on the timing of DLMO, participants will be randomized to eating dinner before DLMO or after DLMO. The investigators will also compare the effects of delaying sleep relative to dinner time. Participants will eat meals in the laboratory and have serial plasma samples collected to examine profiles of free fatty acids, glucose, insulin, triglycerides, and oxidation of dietary fat.

Conditions

  • Healthy

Interventions

BEHAVIORAL

Early dinner

Dinner at DLMO-3, sleep at DLMO+2

BEHAVIORAL

Late Dinner

Dinner at DLMO+1, sleep at DLMO+2

BEHAVIORAL

Late Dinner + Late Sleep

Dinner at DLMO+1, sleep at DLMO+6

Sponsors & Collaborators

  • University of Arkansas

    collaborator OTHER

  • National Marrow Donor Program

    collaborator OTHER

  • Johns Hopkins University

    lead OTHER

Principal Investigators

  • Jonathan Jun, MD · Johns Hopkins University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-01-15
Primary Completion
2025-06-19
Completion
2025-06-19

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04671797 on ClinicalTrials.gov