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Intraoperative Hyperoxia and MINS

NCT04540276 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 7700

Last updated 2021-02-04

No results posted yet for this study

Summary

Oxygen therapy is administered to all patients during general anesthesia to maintain tissue oxygenation and prevent hypoxia and ischemia. However, liberal use of oxygen may lead to hyperoxia and some studies suggest that supranormal levels of arterial oxygen saturation may lead to complications. In this post hoc substudy of the VISION cohort, we plan to assess the association between perioperative inspired oxygen fraction (FiO2) and myocardial injury after non-cardiac surgery (MINS).

Conditions

Interventions

DRUG

Inspiratory oxygen fraction

Median inspiratory oxygen fraction during general anesthesia

Sponsors & Collaborators

  • Population Health Research Institute

    collaborator OTHER

  • University Hospital Bispebjerg and Frederiksberg

    lead OTHER

Principal Investigators

  • Christian S. Meyhoff, MD, PhD · University hospital Bispebjerg Frederiksberg

  • PJ Devereaux, MD, PhD · Population Healt Research Institute

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-02-04
Primary Completion
2020-10-01
Completion
2021-03-01

Countries

  • United States
  • Canada
  • China
  • Colombia
  • Denmark
  • India
  • Malaysia
  • South Africa

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04540276 on ClinicalTrials.gov