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Effects of Hypercapnia on Emergence From General Anesthesia Under Propofol

NCT01531491 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2015-02-16

No results posted yet for this study

Summary

Hypercapnia derives increase of cerebral blood flow and cardiac output. It means that the rate of propofol elimination from the brain and the blood will be increased and the patient will awake more quickly. There has been no study about the effects of hypercapnia. The investigators will evaluate hypercapnia's effects on the recovery time from propofol anesthesia.

Conditions

  • Anesthesia, Intravenous
  • Anesthesia Recovery Period

Interventions

PROCEDURE

Rebreathing tube

750 ml rebreathing tube will be connected between the corrugated tube and the tracheal tube of a patient. Target partial pressure of the end-tidal carbon dioxide is 50 mmHg.

PROCEDURE

No rebreathing tube (Nothing)

750 ml rebreathing tube will not be connected between the corrugated tube and the tracheal tube of a patient. Target partial pressure of the end-tidal carbon dioxide is 30 mmHg.

Sponsors & Collaborators

  • DongGuk University

    lead OTHER

Principal Investigators

  • Junyong In, M.D. · Department of anesthesiology and pain medicine, Dongguk University Ilsan Hospital

Study Design

Allocation
RANDOMIZED
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-01-31
Primary Completion
2013-06-30
Completion
2013-06-30

Countries

  • South Korea

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01531491 on ClinicalTrials.gov