The European NAFLD Registry

Summary

The European NAFLD Registry is a prospectively recruited, observational study supporting the study of the clinical phenotype, natural history, disease outcomes and pathophysiology of Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis. The ultimate goals are to better understand the drivers of interpatient variation in disease pathophysiology and severity and to utilise this information to develop and validate biomarkers that, singly or in combination, enable detection and monitoring of disease progression and/or from NAFL through NASH to fibrosis and cirrhosis.

Conditions

• NAFLD
• NASH
• NASH - Nonalcoholic Steatohepatitis
• Fibrosis, Liver
• Steatosis of Liver
• Hepatocellular Carcinoma
• Cardiovascular Diseases
• Type 2 Diabetes
• Dyslipidaemia
• Hypertension
• Obesity
• Other Associated Comorbidities

Sponsors & Collaborators

• Newcastle-upon-Tyne Hospitals NHS Trust

  collaborator OTHER

• Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

  collaborator OTHER

• Institute of Cardiometabolism and Nutrition, France

  collaborator OTHER

• University of Cambridge

  collaborator OTHER

• Örebro University, Sweden

  collaborator OTHER

• University of Bern

  collaborator OTHER

• University of Oxford

  collaborator OTHER

• University of Turin, Italy

  collaborator OTHER

• University of Angers

  collaborator UNKNOWN

• University Hospital, Antwerp

  collaborator OTHER

• Linkoeping University

  collaborator OTHER_GOV

• University of Helsinki

  collaborator OTHER

• UMC Utrecht

  collaborator OTHER

• National and Kapodistrian University of Athens

  collaborator OTHER

• University of Lisbon

  collaborator OTHER

• University of Milan

  collaborator OTHER

• University of Palermo

  collaborator OTHER

• Catholic University of the Sacred Heart

  collaborator OTHER

• Wuerzburg University Hospital

  collaborator OTHER

• RWTH Aachen University

  collaborator OTHER

• University of Nottingham

  collaborator OTHER

• Medical University of Vienna

  collaborator OTHER

• University of Birmingham

  collaborator OTHER

• University of Florence

  collaborator OTHER

• Assistance Publique - Hôpitaux de Paris

  collaborator OTHER

• University Medical Center Mainz

  collaborator OTHER

• Newcastle University

  lead OTHER

Principal Investigators

• Quentin M Anstee, MBBS, PhD · Newcastle University

Eligibility

Min Age

18 Years

Max Age

100 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2015-05-01

Primary Completion

2030-12-31

Completion

2030-12-31

Countries

• Belgium
• Finland
• France
• Germany
• Greece
• Italy
• Netherlands
• Portugal
• Spain
• Sweden
• Switzerland
• United Kingdom

Study Locations