LITMUS Imaging Study
NCT05479721 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 450
Last updated 2025-04-16
Summary
The LITMUS Imaging Study is a prospectively recruited, observational study of patients with histologically characterised non-alcoholic fatty liver disease (NAFLD). It aims to evaluate the diagnostic performance of imaging biomarkers (ultrasound elastography and magnetic resonance biomarkers) against NAFLD histological scores in a cross-sectional analysis and the natural history of NAFLD in a longitudinal study.
Conditions
- NAFLD
- NASH
- NASH - Nonalcoholic Steatohepatitis
- Fibrosis, Liver
- Steatosis of Liver
Sponsors & Collaborators
-
Newcastle University
collaborator OTHER -
University of Nottingham
collaborator OTHER - collaborator OTHER
-
University of Seville
collaborator OTHER -
Pinnacle Clinical Research, PLLC
collaborator OTHER -
ICAN Nutrition Education and Research
collaborator INDUSTRY -
Assistance Publique - Hôpitaux de Paris
collaborator OTHER -
University of Angers
collaborator UNKNOWN -
University of Palermo
collaborator OTHER -
University of Turin, Italy
collaborator OTHER -
University Medical Center Mainz
collaborator OTHER -
University of Helsinki
collaborator OTHER -
University of Bern
collaborator OTHER -
Linkoeping University
collaborator OTHER_GOV -
Perspectum
collaborator INDUSTRY -
Antaros Medical
collaborator INDUSTRY -
Resoundant Inc
collaborator UNKNOWN - collaborator INDUSTRY
- collaborator INDUSTRY
- collaborator INDUSTRY
-
Intercept Pharmaceuticals
collaborator INDUSTRY -
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
collaborator OTHER - collaborator INDUSTRY
-
University of Oxford
lead OTHER
Principal Investigators
-
Michael Pavlides, MBBS, DPhil · University of Oxford
Eligibility
- Min Age
- 18 Years
- Max Age
- 100 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-09-04
- Primary Completion
- 2025-10-31
- Completion
- 2025-10-31
Countries
- United States
- Finland
- France
- Germany
- Greece
- Italy
- Spain
- Sweden
- Switzerland
- United Kingdom
Study Locations
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