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Evaluation of Static Postural Balance in Children With Hemophilia and Its Relationship With Joint Health

NCT04406519 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 42

Last updated 2020-05-28

No results posted yet for this study

Summary

Hemophilia is a rare hematological disorder characterized by a partial or complete deficiency of clotting factor VIII or IX.Bleeding disorders mainly affect the musculoskeletal system. Intra-articular bleeding is an important complication related to hemophilia and usually occurs in large synovial joints such as knees and ankles. Initially, these bleeds occur non-specific spontaneously and usually affect one joint, and repeated bleeding makes that joint a target joint. Postural balance can be defined as the ability to maintain a stable posture for maximum duration with minimal body sway, or to hold the body centre of gravity (CoG) over its base support in varying conditions (1). Somatosensorial information from mechanoreceptors, visual and vestibular receptors is required to maintain postural balance. Postural balance is tried to be controlled by the postural adjustments provided by the contraction of the lower limb muscles and trunk muscles before perturbation. Spontaneous hemarthrosis is a distinctive feature of severe haemophilia, and that recurrent bleedings may likely to cause postural balance disorders by disrupting proprioceptive inputs from mechanoreceptors in the joint. Data on how bleeding affects postural balance in children with hemophilia is unclear.In the relationship between the clinical evaluation of hemophilia and postural balance, there is little research in the literature.

Conditions

  • Hemophilia
  • Arthropathy of Knee
  • Arthropathy of Ankle or Foot

Sponsors & Collaborators

  • Necmettin Erbakan University

    lead OTHER

Principal Investigators

  • Ahmet Fayik Oner, Prof. · Van Yuzuncu Yil University Faculty of Medicine Dept of Pediatric Hematology

  • Kamuran Karaman, Assoc. Prof. · Van Yuzuncu Yil University Faculty of Medicine Dept of Pediatric Hematology

  • Seyhmus Kaplan, Assoc. Prof. · Van Yuzuncu Yil University Faculty of Medicine Dept of Sports Medicine

Eligibility

Min Age
6 Years
Max Age
18 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-02-01
Primary Completion
2018-07-01
Completion
2019-05-15

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04406519 on ClinicalTrials.gov