Alterations in Coagulation Factor Levels in Patients With End Stage Liver Disease
NCT06014320 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 25
Last updated 2023-08-28
Summary
The goal of this observational study is to learn about the changes in coagulation factor VIII and IX levels in patients undergoing liver transplantation to help guide future management of coagulation factor replacement in patients with hemophilia and liver disease. The question we aim to answer is: should the recommendations for factor replacement in patients with hereditary bleeding disorders be altered in the setting of end stage liver cirrhosis?
Participants will be asked to provide two blood samples, one at the beginning of their liver transplant, and one after their liver transplant.
Conditions
- Liver Cirrhosis
- Hemophilia
- Hemophilia A
- Hemophilia B
- Liver Transplant Disorder
- Liver Failure
- Coagulation Factor Deficiency
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Alexandra Ruan, MD · Stanford University
-
Martin Angst, MD · Stanford University
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-10-01
- Primary Completion
- 2024-04-01
- Completion
- 2024-10-01
Countries
- United States
Study Locations
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