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Transfusion-Associated Microchimerism in Previously Injured Individuals Who Received a Blood Transfusion

NCT00441779 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 59

Last updated 2016-07-12

No results posted yet for this study

Summary

Blood transfusions are frequently necessary in situations in which there is a large amount of blood loss. In some individuals who receive a blood transfusion, white blood cells from the donor's blood may remain in the body for years, a condition known as microchimerism. This study will evaluate the occurrence of microchimerism among the following three groups of individuals who previously received transfusions: 1) individuals with traumatic injuries; 2) individuals with burn injuries; and 3) individuals who underwent elective orthopedic operations.

Conditions

  • Chimerism
  • Blood Transfusion
  • Wounds and Injuries

Sponsors & Collaborators

  • National Heart, Lung, and Blood Institute (NHLBI)

    lead NIH

Principal Investigators

  • Michael P. Busch, MD, PhD · Vitalant Research Institute

Eligibility

Min Age
8 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-08-31
Primary Completion
2011-10-31
Completion
2011-10-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00441779 on ClinicalTrials.gov