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The Effect of Tranexamic Acid in Total Blood Loss During Proximal Femoral Nailing

NCT05359172 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2022-10-10

No results posted yet for this study

Summary

Blood loss is an important issue following intertrochanteric femoral fracture and may lead to requiring blood transfusions and transfusion complications. Tranexamic acid is a commonly used drug to decrease blood loss and the number of transfusions. The aim of our study is to determine the effectiveness of tranexamic acid use to reduce total blood loss during proximal femoral nailing for the intertrochanteric femoral fracture in the elderly.

Patients aged \>65 years and diagnosed with intertrochanteric fracture will be included in the study. The patients will be numbered according to the admission to the hospital and randomly divided into two groups. First group will receive tranexamic acid infusion and second group will not receive tranexamic acid infusion. Total blood loss will be calculated using Nadler formula. The primary outcome of the study is total blood loss. The secondary outcomes are a number of transfusions, and surgical blood loss during the operative procedure.

Conditions

  • Hip Fractures
  • Intertrochanteric Fractures
  • Blood Loss

Interventions

DRUG

Tranexamic acid

preoperative intravenous infusion

Sponsors & Collaborators

  • Haseki Training and Research Hospital

    lead OTHER

Eligibility

Min Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-04-01
Primary Completion
2022-07-09
Completion
2022-07-10

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05359172 on ClinicalTrials.gov