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Topical Tranexamic Acid and Acute Blood Loss in Total Knee Arthroplasty

NCT01370460 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 101

Last updated 2023-04-25

Study results available
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Summary

This study aims to assess postoperative blood loss and transfusion rates in total knee replacement after one-time administration of topical tranexamic acid.

Conditions

  • Acute Blood Loss Anemia
  • Osteoarthritis, Knee

Interventions

DRUG

Tranexamic Acid

Topical tranexamic acid (2g/100mL 0.9% saline)

DRUG

Placebo

100mL 0.9% sterile saline

Sponsors & Collaborators

  • Henry Ford Health System

    lead OTHER

Principal Investigators

  • Michael Laker, M.D. · Henry Ford Health System

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-06-30
Primary Completion
2012-09-30
Completion
2012-09-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01370460 on ClinicalTrials.gov