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Netosis in Determination of Respiratory Infection Severity

NCT04318691 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 80

Last updated 2023-03-16

No results posted yet for this study

Summary

The study aims to evaluate the prognostic value of alveolar and blood NETosis in patients under mechanical ventilation and treated for an acute low-respiratory tract infection. The main outcome is the occurrence of an acute respiratory distress syndrome (ARDS) according to the Berlin definition.

Conditions

  • Respiratory Infection

Interventions

BIOLOGICAL

Blood sampling

Blood sampling at baseline and at day-3 (10 ml, EDTA tube), test of NETs.

PROCEDURE

Bronchoalveolar lavage

Bronchoalveolar lavage at admission to the ICU with analysis of cytological, bacteriological, viral and anatomopathological, and test of NETs.

Sponsors & Collaborators

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Principal Investigators

  • Edouard JULLIEN, MD · Service de médecine intensive réanimation, Hôpital Ambroise Paré, APHP

  • Guillaume Geri, MD, PhD · Service de médecine intensive réanimation, Hôpital Ambroise Paré, APHP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-06-07
Primary Completion
2023-01-03
Completion
2023-01-03

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04318691 on ClinicalTrials.gov