MedTrace Logo

Effects of Invasive Mechanical Ventilation on the Right Ventricular Function

NCT05710419 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2023-02-02

No results posted yet for this study

Summary

The goal of this observational study is to learn about the influence of mechanical ventilation on the right ventricular (RV) function. The primary focus is on methods which are routinely used to improve gas exchange in ventilated patients (positive end expiratory pressure \[PEEP\], inhalation of NO, prone positioning). The main questions it aims to answer are:

* Effects of prone positioning, PEEP and inhalation of NO on RV-function
* Are there determinants (clinical, laboratory, demographic, echocardiographic) for the right ventricular response to the above?

RV-Function will be assessed with right ventricular pressure-volume loops recorded with a conductance catheter at

* each PEEP-Level during titration of the best PEEP
* before and every 5 minutes (for max. 45 minutes) after rotation to prone position
* before and under continuous inhalation of NO (if required based on clinical grounds)

Conditions

Sponsors & Collaborators

  • University of Giessen

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-11-04
Primary Completion
2024-11-04
Completion
2024-11-04

Countries

  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05710419 on ClinicalTrials.gov