Comparison Between Limited Driving Pressure Ventilation and Conventional Mechanical Ventilation Strategies in Medical Intensive Care Patients With Acute Respiratory Failure
NCT04035915 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 126
Last updated 2021-09-24
Summary
Background An appropriated mechanical ventilator setting for acute respiratory failure results of ventilator associated lung injury. Limited driving pressure and low tidal volume ventilation strategies show benefits decreasing mortality in acute respiratory distress syndrome, but there are no data in simple acute respiratory failure.
Conditions
- on Invasive Mechanical Ventilation
- ARDS
- Respiratory Failure
Interventions
- PROCEDURE
-
Limited driving pressure
Keep driving pressure \<15 cmH2O
- PROCEDURE
-
Conventional mechanical ventilation strategies
Keep tidalvolume \</= 8
Sponsors & Collaborators
-
Mahidol University
lead OTHER
Principal Investigators
-
Surat Tongyoo, MD · Mahidol University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-07-25
- Primary Completion
- 2020-12-31
- Completion
- 2021-03-31
Countries
- Thailand
Study Locations
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