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Oral and Systemic aMMP-8 in Periodontal Disease

NCT04268381 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 83

Last updated 2020-07-14

No results posted yet for this study

Summary

Periodontal disease is an inflammatory process that can result in tooth loss and also is considered a modifying factor for systemic health. Matrix metalloproteinase (MMP)-8 is the major collagenase of periodontal tissue breakdown. The aim of the present study is to analyze active (aMMP-8) levels in gingival crevicular fluid (GCF), saliva and serum in the context of new criteria of gingivitis and stage 3 grade C periodontitis.

Conditions

  • Periodontal Diseases
  • Periodontal Inflammation

Interventions

OTHER

Biochemical analysis

aMMP-8 is measured by immunofluorometric assay (IFMA).

Sponsors & Collaborators

  • Giresun University

    collaborator OTHER

  • Aydin Adnan Menderes University

    lead OTHER

Principal Investigators

  • Zeynep Pinar Keles Yucel · Department of Periodontology, School of Dentistry, Giresun University

Eligibility

Min Age
25 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-01-20
Primary Completion
2020-03-20
Completion
2020-03-20

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04268381 on ClinicalTrials.gov