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The Effects of Esmolol on the Hemodynamic Response to Orotracheal Extubation

NCT04264286 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2020-02-11

No results posted yet for this study

Summary

Beta-blockers are useful tools for the prevention of hemodynamic instability in the manipulation of airways. The main objective of the present study is to evaluate the effectiveness of using esmolol in attenuating hemodynamic responses at the time of tracheal extubation, by assessing the incidence of tachycardia in relation to placebo.

Conditions

  • Beta Blocker
  • Hemodynamic Instability

Interventions

DRUG

Prophylactic esmolol

Patients will receive prophylactic esmolol after the end of the surgery

DRUG

Placebo

Patients will prophylactic placebo after the end of the surgery

Sponsors & Collaborators

  • Hospital de Base

    lead OTHER

Principal Investigators

  • Fabricio T Mendonça, MD, MSc · Hospital de Base do Distrito Federal

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-07-01
Primary Completion
2020-07-31
Completion
2020-07-31

Countries

  • Brazil

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04264286 on ClinicalTrials.gov