Prospective Study of Induction Medications Used in the Trauma RSI
NCT04291521 · Status: WITHDRAWN · Type: OBSERVATIONAL
Last updated 2026-05-04
Summary
To compare the outcomes of the use of propofol, etomidate, and ketamine as induction agents for adult trauma patients undergoing intubation within 24 hours of admission. The primary goal is to determine the ideal agent that should be used in this patient population for intubations.
Conditions
- Trauma
- Rapid Sequence Intubation
Interventions
- DRUG
-
Administering ketamine as an induction medication for intubating adult trauma patients within 24 hours of hospital admission.
- DRUG
-
Etomidate
Administering etomidate as an induction medication for intubating adult trauma patients within 24 hours of hospital admission.
- DRUG
-
Propofol
Administering propofol as an induction medication for intubating adult trauma patients within 24 hours of hospital admission.
Sponsors & Collaborators
-
University of California, Irvine
collaborator OTHER -
University of Texas
collaborator OTHER -
University of Chicago
collaborator OTHER -
Medical College of Wisconsin
collaborator OTHER -
University of Southern California
lead OTHER
Principal Investigators
-
Catherine M Kuza, MD · Keck School of Medicine of the University of Southern California
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2027-01-01
- Primary Completion
- 2029-04-30
- Completion
- 2029-07-30
Countries
- United States
Study Locations
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