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Effects of Phytonutrients on Vascular Health

NCT02605850 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 32

Last updated 2020-01-02

No results posted yet for this study

Summary

This study will determine the effects of beneficial compounds of plant foods, such as pomegranate on cardiovascular health. This will be tested by asking healthy males to eat a high fat ground beef patty with pomegranate juice (PJ), pomegranate extract (PomX) or water and then measuring blood vessel dilation (endothelial function) by blood flow We also will measure the amount of Nitric Oxide (NO) in your blood and urine samples and sugar and insulin in blood. Healthy men have been chosen for this study because eating high fat hamburger patties can easily mimic in them the condition that causes atherosclerosis. The results from this study may help to explain how high fat foods can be harmful to the body and how beneficial plant foods can have on cardiovascular function

Conditions

Interventions

OTHER

Water

All subjects will consume ground beef patty meal with water at the baseline visit.

DIETARY_SUPPLEMENT

Pomegranate Juice

Pomegranate Juice will be taken 1/day for 4 weeks.

DIETARY_SUPPLEMENT

Pomegranate extract

Pomegranate extract will be taken 1/day for 4 weeks.

Sponsors & Collaborators

Principal Investigators

  • Zhaoping Li, MD, PhD · University of California, Los Angeles

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-01-31
Primary Completion
2016-09-30
Completion
2016-09-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02605850 on ClinicalTrials.gov