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Cerebellar rTMS Theta Burst for Postural Instability in Progressive Supranuclear Palsy

NCT04222218 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2020-01-22

No results posted yet for this study

Summary

Objective of the study:

To test the efficacy of theta burst cerebellar stimulation on postural instability in progressive supranuclear palsy using a cross-over design and wearing sensors technology

Design:

Twenty probable PSP patients with no dementia and still able to walk will be recruited for a cross-over sham-controlled study. Each patient will undergo a sham stimulation or a single session of cerebellar theta burst stimulation with a wash out period of at least 14 days.

Each patient will be evaluated before and after stimulation by berg balance tests (BBS), Tinetti scale, PSP-rating scale (PSP-RS), and a battery of gait and movement tests.

Static balance was assessed by 30-seconds-trials in semitandem and tandem positions with eyes open and closed using wearing sensors technology.

Conditions

Interventions

DEVICE

repetitive transcranial magnetic stimulation

Cerebellar repetitive theta Burst stimulation will be performed as detailed in the Real arm description

Sponsors & Collaborators

  • University of Brescia, Neurology Department

    collaborator UNKNOWN

  • University of Kiel, Neurogeriatric Department

    collaborator UNKNOWN

  • Fondazione Europea di Ricerca Biomedica Ferb Onlus

    lead OTHER

Principal Investigators

  • Andrea Pilotto, MD · Università degli Studi di Brescia

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
40 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-06-01
Primary Completion
2019-11-01
Completion
2019-11-15

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04222218 on ClinicalTrials.gov