Cerebellar High-Frequency rTMS in Balance of Multiple Sclerosis Patients
NCT06998810 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2025-05-31
Summary
Background: Multiple Sclerosis (MS) is a chronic autoimmune disease affecting the central nervous system (CNS), leading to progressive motor dysfunction and balance deficits. Objective: To investigate the impact of cerebellar rTMS in improving postural control, balance performance and functional ambulation in individuals with MS.
Forty patients were randomly assigned to receive repetitive transcranial magnetic stimulation (rTMS) over the cerebellum to improve motor function and balance in 40 MS patients. Outcome measures, including the Expanded Disability Status Scale (EDSS), static posturography (COP measures), the International Cooperative Ataxia Rating Scale (ICARS), and the 10-Meter Walk Test (10MWT), were assessed before and after intervention.
Conditions
Interventions
- DEVICE
-
cerebellar rTMS
Non-invasive magnetic stimulation targeting the cerebellum using a figure of eight coil
Sponsors & Collaborators
-
Ain Shams University
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-02-25
- Primary Completion
- 2024-12-25
- Completion
- 2025-03-25
Countries
- Egypt
Study Locations
More Related Trials
-
Non-invasive Cerebellar Stimulation on Motor Learning
NCT02559518 ·Status: COMPLETED ·Phase: NA
-
Cerebellar Non-invasive Stimulation in Ataxias
NCT03213106 ·Status: UNKNOWN ·Phase: NA
-
Movement Disorders in Multiple Sclerosis Patients
NCT05973929 ·Status: UNKNOWN
-
Cerebellar rTMS Theta Burst for Postural Instability in Progressive Supranuclear Palsy
NCT04222218 ·Status: COMPLETED ·Phase: NA
-
Cerebellar rTMS and Physical Therapy for Cerebellar Ataxia
NCT04595578 ·Status: COMPLETED ·Phase: NA
-
Auditory-motor Coupling in Multiple Sclerosis With Cerebellar Lesions
NCT04639401 ·Status: COMPLETED ·Phase: NA
-
Effect of Hypnosis on Motor Cortex Excitability
NCT00416247 ·Status: COMPLETED ·Phase: NA
-
Functional and Structural Imaging and Motor Control in Spinocerebellar Ataxia
NCT02488031 ·Status: COMPLETED ·Phase: NA
-
Cognitive-motor Dual Task Training in Patients With Multiple Sclerosis
NCT04619953 ·Status: COMPLETED ·Phase: NA
-
Repetitive Transcranial Magnetic Stimulation in Essential Tremors Patients
NCT05157321 ·Status: COMPLETED ·Phase: NA
-
Investigating Cerebellar Inhibition and Its Clinical Significance in Parkinsonian Tremor and Intention Tremor
NCT05512299 ·Status: UNKNOWN
-
Use of Real-Time Functional Magnetic Resonance Imaging Neurofeedback to Improve Motor Function in Cerebellar Ataxia
NCT05436249 ·Status: COMPLETED ·Phase: NA
-
Validity and Reliability of the L Test in Single and Dual Task Conditions in Multiple Sclerosis
NCT07186998 ·Status: COMPLETED
-
Effect of Motor Cortex Versus Sacral Magnetic Stimulation in Multiple Sclerosis Patients With Urinary Tract Dysfunction
NCT03434873 ·Status: COMPLETED ·Phase: NA
-
Using Real-time fMRI Neurofeedback and Motor Imagery to Enhance Motor Timing and Precision in Cerebellar Ataxia
NCT05436262 ·Status: COMPLETED ·Phase: NA
-
Characterization of Executive Functions and Patterns of Eye Movements in Children With Developmental Disabilities
NCT00716235 ·Status: UNKNOWN
-
The Effect of Whole Body Vibration Training on Neuromuscular Property in Individuals With Ataxia
NCT01983631 ·Status: COMPLETED ·Phase: NA
-
Neurophysiology of Surround Inhibition in the Human Motor Cortex
NCT03018262 ·Status: COMPLETED
-
Transcranial Magnetic Stimulation in Spino-Cerebellar Ataxia
NCT01975909 ·Status: COMPLETED ·Phase: NA
-
To Explore the Neural Processing Mechanism of Cerebellum Involved in Facial Expression Recognition Based on Transcranial Magnetic Stimulation
NCT06860451 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Effects of Cerebellum or Supplementary Motor Area Functional Inactivation on Gait and Balance Control
NCT02976298 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
The Effects of Bilateral Cerebellar rTMS on Cortical Function
NCT03831789 ·Status: COMPLETED ·Phase: NA
-
Effects of A Dual-Task Intervention in Postural Control in Multiple Sclerosis Patients
NCT04090996 ·Status: UNKNOWN ·Phase: NA
-
Dual Task Cost in the Upper Limb in Persons With Multiple Sclerosis
NCT02493166 ·Status: COMPLETED ·Phase: NA
-
Psychometric Properties Upper Limb Function Measures Multiple Sclerosis
NCT02339675 ·Status: COMPLETED ·Phase: NA