MedTrace Logo

Verticality Perception - Multisensory Contribution

NCT02212704 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2024-11-01

No results posted yet for this study

Summary

The purpose of this study is to evaluate the relative contribution of head- and trunk-based sensory systems to internal estimates of direction of gravity in healthy human subjects. To implement this assessment experimentally, the investigators will use a motor-driven 3D-turntable and a thermoplastic mask to keep the head in a stable, either roll-tilted (±30°) or aligned with the trunk. The investigators will then obtain measurements of the subjective visual vertical in seven different whole-body roll positions (max. 90° roll-tilt). Analysis will be driven by a state-of-the art Bayesian integration model. The investigators hypothesize that different sensory input signals are combined in a statistically optimal fashion.

Conditions

  • Verticality Perception in Healthy Human Subjects
  • Individual Contribution of Different Sensory Systems

Interventions

OTHER

Vestibular stimulation by use of the turntable (static roll-tilt while the head is roll-tilted relative to the trunk)

OTHER

3D-video-head impulse testing

Evaluation of semicircular canal function. This intervention is part of the screening to determine suitability for this study

OTHER

Vestibular-evoked myogenic potentials (VEMPs)

Evaluation of otolith function. This intervention is part of the screening to determine suitability for this study

Sponsors & Collaborators

  • University of Zurich

    lead OTHER

Principal Investigators

  • Dominik Straumann, Prof, MD · University Hospital Zurich, Dept. of Neurology

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-10-31
Primary Completion
2015-11-30
Completion
2015-11-30

Countries

  • Switzerland

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02212704 on ClinicalTrials.gov