FTO Gene Variants and Diet in Obesity
NCT04205318 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 400
Last updated 2019-12-19
Summary
Studies have shown that the effect of fat mass and obesity-associated (FTO) gene on obesity is modulated by lifestyle factors. Hence, we aimed to determine whether two single nucleotide polymorphisms (SNPs) in the FTO gene are associated with obesity and to assess whether these associations were modified by lifestyle factors. The study included 200 obese and 200 non-obese individuals from Turkey. Our study suggests that the effect of the SNPs on obesity traits is likely to be influenced by lifestyle factors in this Turkish population.
Conditions
- Obesity
- Diet Habit
- Genetic Predisposition
Sponsors & Collaborators
-
University of Reading
collaborator OTHER -
The Scientific and Technological Research Council of Turkey
collaborator OTHER -
Hacettepe University
lead OTHER
Principal Investigators
-
Zehra Buyuktuncer · Hacettepe University, Department of Nutrition and Dietetics, Ankara, TURKEY
-
Vimales Karani Santhanakrishnan · Department of Food and Nutritional Sciences, University of Reading, UK
Eligibility
- Min Age
- 24 Years
- Max Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2017-03-01
- Primary Completion
- 2018-02-01
- Completion
- 2018-12-31
Countries
- Turkey (Türkiye)
Study Locations
More Related Trials
-
Genetics of Obesity in Chinese Youngs
NCT01084967 ·Status: RECRUITING
-
Variation of Genes Controlling Carbohydrate and Lipid Metabolism
NCT03310502 ·Status: UNKNOWN
-
Investigation of Genetic Marker Associated With Obesity in Koreans
NCT01341860 ·Status: TERMINATED
-
Balanced Nutritional Diet Intervention Among Obese Women
NCT06442202 ·Status: COMPLETED ·Phase: NA
-
Interaction of Genetic and Environmental Factors for Body Fat Mass Control
NCT04299698 ·Status: COMPLETED
-
Leipzig Childhood Obesity Study
NCT04491344 ·Status: RECRUITING
-
Weight Loss and CLOCK 3111T/C Polymorphism
NCT05750732 ·Status: RECRUITING
-
Sequencing of 14 Genes From Leptin Melanocortin Pathway in Severe Obesity in Childhood.
NCT05938335 ·Status: UNKNOWN ·Phase: NA
-
Genetic Pathways Leading to Fatty Liver and Atherogenic Dyslipidemia
NCT04209816 ·Status: ENROLLING_BY_INVITATION
-
Gene Expression and Inflammation in Overweight Subjects
NCT00344266 ·Status: COMPLETED
-
An Observational,Prospective Natural History Study of Early-Onset Extreme Obesity Due to Bi-Allelic Loss-of-Function Mutations in the POMC, PCSK1 or LEPR Genes
NCT03621007 ·Status: COMPLETED
-
Metabolic Flexibility, Gut Microbiota, Healthy Diet and Exercise in NAFLD on Genetics Base
NCT02951546 ·Status: COMPLETED ·Phase: NA
-
Study of the Role of PCSK9 and FXR in the Physiopathology of the Joint Dyslipidemia Associated to the Human Immunoresistance
NCT00422006 ·Status: COMPLETED ·Phase: NA
-
Dietary Intervention and Assessment of Obesity-related Gene Methylation Levels in Overweight Women
NCT04523532 ·Status: COMPLETED ·Phase: NA
-
Frequency of ICAM-1 Polymorphisms in Obese Subjects
NCT00436488 ·Status: COMPLETED
-
Dynamics of Gut Microbiome in Overweight or Obese Participants on a Modified Atkins Diet
NCT07212556 ·Status: WITHDRAWN
-
Dietary, Physiological, Genetic, and Behavioral Predictors of Health in a Young, Ethnically-Mixed Population
NCT00945633 ·Status: ACTIVE_NOT_RECRUITING
-
Physical and Behavioral Traits of Overweight and Obese Adults
NCT00428987 ·Status: RECRUITING
-
The Effects of Environmental Factors on the Macro-genome and Metabolism of Obese Patients.
NCT06673433 ·Status: ACTIVE_NOT_RECRUITING
-
Diet-Induced-Obesity Resistant Phenotypes in Humans
NCT00999154 ·Status: TERMINATED
-
Personalised Medicine for Morbid Obesity
NCT01365416 ·Status: ACTIVE_NOT_RECRUITING
-
Impact of Health Lifestyle on Body Weight
NCT05608226 ·Status: UNKNOWN
-
Gut Microbiome and Obesity
NCT04451148 ·Status: UNKNOWN
-
Genetics of Fatty Liver Disease in Children
NCT01966627 ·Status: COMPLETED
-
Genetic Research of Monogenic Obesity in a Pediatric Cohort With Severe and Early Onset Obesity (GENOBE)
NCT06113523 ·Status: NOT_YET_RECRUITING