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Gut Microbiome and Obesity

NCT04451148 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 120

Last updated 2020-07-07

No results posted yet for this study

Summary

Pediatric obesity is a risk factor for the onset of obesity in adulthood and is a risk factor for various chronic non-communicable diseases. Metabolic syndrome (MS) is the name for a group of risk factors that increase cardiovascular risk and other health problems characterized by the presence of abdominal obesity, dyslipidemia, hyperglycaemia and high blood pressure. Numerous preclinical and clinical data suggest a potential role of the intestinal microbiota in these diseaes. Unfortunately, comparative studies of the gut microbiota are still scarce in pediatric subjects suffering from obesity than obesity complicated by MS. The aim is to study the metagenomics and metabolomics characteristics of the intestinal microbiota in obese children/adolescents with or without MS, that could provide useful data for innovative intervention strategies for these conditions.

Conditions

  • Obesity, Childhood
  • Metabolic Syndrome

Interventions

OTHER

Obese with or without metabolic syndromesubjects

Children with obesity and with or without metabolic syndrome

Sponsors & Collaborators

  • Federico II University

    lead OTHER

Eligibility

Min Age
10 Years
Max Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-05-01
Primary Completion
2022-05-01
Completion
2022-05-01

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04451148 on ClinicalTrials.gov