Association Between the Change of the Genes With Hormones and Food Consumption of Obese
NCT02598037 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 71
Last updated 2018-05-02
Summary
Obesity is considered one of the most troubling chronic diseases for public health because of its rapid growth in the population. Many are the causal factors of this epidemic, and in recent years studies suggest the involvement of genetic factors in the etiology of obesity as a risk factor for its development. Polymorphism of the FTO gene is being studied in the past eight years and has been indicated as a predictor of obesity in the population, as well as associations in food intake, raising the possibility of influence in the regulation of hunger and satiety. Accordingly, researchers observed changes in levels of postprandial leptin and ghrelin, which can promote appetite and change the quantity and quality of food intake in subjects with the polymorphism FTO.
Conditions
Interventions
- DIETARY_SUPPLEMENT
-
Test meal
The test meal will contain the following features: 50% carbohydrate, 20% protein and 30% of total fat, and will be admnistrada after drawing blood fasting for 12 hours.
Sponsors & Collaborators
-
Universidade Federal do Rio de Janeiro
lead OTHER
Principal Investigators
-
Fernanda CM Magno, MSc · Universidade Federal do Rio de Janeiro
Study Design
- Allocation
- NA
- Purpose
- HEALTH_SERVICES_RESEARCH
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 20 Years
- Max Age
- 50 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-09-30
- Primary Completion
- 2017-10-31
- Completion
- 2017-12-31
Countries
- Brazil
Study Locations
More Related Trials
-
Sequencing of 14 Genes From Leptin Melanocortin Pathway in Severe Obesity in Childhood.
NCT05938335 ·Status: UNKNOWN ·Phase: NA
-
The Effects of Environmental Factors on the Macro-genome and Metabolism of Obese Patients.
NCT06673433 ·Status: ACTIVE_NOT_RECRUITING
-
Elucidating Growth Hormone Dynamics at Stages of Progressive Nonalcoholic Fatty Liver Disease
NCT06166797 ·Status: NOT_YET_RECRUITING
-
Effect of Oral Feeding on Gastric Emptying, Gut Blood Flow, and Hormone Responses in Obese and Healthy Weight Subjects
NCT03860623 ·Status: COMPLETED
-
Long Term Effects of Weight Loss on Post-prandial Gut Hormone Responses and Meal Induced Thermogenesis
NCT04170010 ·Status: UNKNOWN
-
Effect of Exercise on Appetite, Gut Peptides and Butyrylcholinesterase Activity in Variants of the FTO Gene
NCT03025347 ·Status: COMPLETED ·Phase: NA
-
Genetics of Obesity in Chinese Youngs
NCT01084967 ·Status: RECRUITING
-
Genetic Influences Between Cognitive Function and BMI
NCT03116334 ·Status: COMPLETED
-
Genetic Determinants and Clinical Consequences of Early-onset Severe Obesity
NCT02645422 ·Status: UNKNOWN
-
Abdominal Obesity, Cardiovascular Inflammation, and Effects of Growth Hormone Releasing Hormone Analogue
NCT01632592 ·Status: WITHDRAWN ·Phase: NA
-
Variation of Genes Controlling Carbohydrate and Lipid Metabolism
NCT03310502 ·Status: UNKNOWN
-
Polymorphids an mRNA Expression in Obese Genes
NCT01708083 ·Status: COMPLETED
-
Dietary Intervention and Assessment of Obesity-related Gene Methylation Levels in Overweight Women
NCT04523532 ·Status: COMPLETED ·Phase: NA
-
Cytokine and Body Composition's Changes in Overweight/Obese Women
NCT02766426 ·Status: UNKNOWN ·Phase: NA
-
Investigation of Genetic Marker Associated With Obesity in Koreans
NCT01341860 ·Status: TERMINATED
-
Gene Expression and Inflammation in Overweight Subjects
NCT00344266 ·Status: COMPLETED
-
Obesity and Nonalcoholic Fatty Liver Disease
NCT00262964 ·Status: COMPLETED ·Phase: NA
-
Anthropometric Assessment of Abdominal Obesity and Health Risk in Children and Adolescents
NCT01595100 ·Status: COMPLETED
-
Physical Activity Level and Hormonal Status on Energy Metabolism and Nutritional Responses
NCT05944653 ·Status: UNKNOWN
-
Dietary, Physiological, Genetic, and Behavioral Predictors of Health in a Young, Ethnically-Mixed Population
NCT00945633 ·Status: ACTIVE_NOT_RECRUITING
-
Molecular, Cellular, and Genetic Characterization of Human Adipose Tissue and Its Role in Metabolism
NCT02692885 ·Status: RECRUITING
-
Metabolic Phenotyping for Personalized Obesity Therapy
NCT06874270 ·Status: RECRUITING
-
Metabolically Normal and Metabolically Abnormal Obesity
NCT01184170 ·Status: COMPLETED ·Phase: NA
-
The Food Intake Phenotype: Assessing Eating Behavior and Food Preferences as Risk Factors for Obesity
NCT00342732 ·Status: COMPLETED
-
Diet-Induced-Obesity Resistant Phenotypes in Humans
NCT00999154 ·Status: TERMINATED