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Surgical Innovation for Diabetes Treatment

NCT04196348 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2022-09-02

No results posted yet for this study

Summary

This study will determine how two variants of gastric bypass induce changes in dynamic endocrine response in the fasting and post-prandial state, both before and at different time points after the surgical interventions.

This study will monitor the endocrine dynamics after different anatomical modifications produced by Roux-en-Y gastric bypass procedures in diabetic participants and normoglycemic participants, to gain insights into the mechanisms beyond the metabolic improvement after the two surgical variants through participants re-evaluation at different time points.

Conditions

  • Obesity
  • Diabetes Mellitus, Type 2

Interventions

PROCEDURE

Short BPL RYGB

Alimentary limb (AL) with 120 cm and BPL with 100 cm.

PROCEDURE

Long BPL RYGB

AL with 120 cm and BPL with 200 cm.

Sponsors & Collaborators

  • Instituto de Ciências Biomédicas Abel Salazar

    collaborator OTHER

  • The Novo Nordisk Foundation Center for Basic Metabolic Research

    collaborator OTHER

  • Hospital de Sao Sebastiao

    lead OTHER

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-03-28
Primary Completion
2020-08-31
Completion
2024-08-31

Countries

  • Portugal

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04196348 on ClinicalTrials.gov