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Influence of Gut Hormones on Food Intake After Roux-en-Y Gastric Bypass Surgery

NCT02336659 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2016-06-21

No results posted yet for this study

Summary

The aim of this study is to examine the effect of GLP-1 and other gut-secreted hormones (glucagon, GIP, grelin and PYY) on food-intake, appetite and glucose metabolism after Roux-en-Y gastric bypass surgery.

Conditions

Interventions

DRUG

exendin 9-39

Exendin 9-39 is a specific GLP-1 receptor antagonist

DRUG

sitagliptin

DPP-4 Inhibition

OTHER

Placebo

Saline

Sponsors & Collaborators

  • University of Copenhagen

    collaborator OTHER

  • Hvidovre University Hospital

    lead OTHER

Principal Investigators

  • Sten Madbad, MD, DMSc · Hvidovre University Hospital

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-04-30
Primary Completion
2016-05-31
Completion
2016-06-30

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02336659 on ClinicalTrials.gov