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Calcium for Out-of-Hospital Cardiac Arrest

NCT04153435 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 397

Last updated 2022-07-25

Study results available
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Summary

This is an investigator-initiated, multicenter, randomized, placebo-controlled, parallel group, double-blind, superiority trial of calcium during adult out-of-hospital cardiac arrest. 430 adult patients with out-of-hospital cardiac arrest receiving at least one dose of adrenaline will be enrolled. The primary outcome is sustained return of spontaneous circulation and key secondary outcomes include survival at 30 days and survival at 30 days with a favorable neurological outcome.

Conditions

  • Heart Arrest, Out-Of-Hospital

Interventions

DRUG

Calcium Chloride

Calcium chloride 5 mmol

DRUG

Sodium chloride 0.9%

Placebo

Sponsors & Collaborators

  • Central Denmark Region

    collaborator OTHER

  • University of Aarhus

    collaborator OTHER

  • Lars Wiuff Andersen

    lead OTHER

Principal Investigators

  • Lars W Andersen · Aarhus University Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-01-20
Primary Completion
2021-04-15
Completion
2022-04-15

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04153435 on ClinicalTrials.gov