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Advanced Reperfusion Strategies for Refractory Cardiac Arrest

NCT03880565 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2022-03-10

Study results available
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Summary

This is a Phase II, single center (Under the Center for Resuscitation Medicine at the University of Minnesota Medical School), partially blinded, prospective, intention to treat, safety and efficacy clinical trial, randomizing adult patients (18-75 years old) with refractory ventricular fibrillation/pulseless ventricular tachycardia (VF/VT) out-of hospital cardiac arrest (OHCA) who are transferred by emergency medical services (EMS) with ongoing mechanical cardiopulmonary resuscitation (CPR) or who are resuscitated to receive one of the 2 local standards of care practiced in our community: 1) Early Extracorporeal Membrane Oxygenation (ECMO) Facilitated Resuscitation or 2) Standard Advanced Cardiac Life Support (ACLS) Resuscitation

Conditions

  • Cardiac Arrest
  • Extracorporeal Membrane Oxygenation Complication
  • Ventricular Fibrillation
  • Pulseless Ventricular Tachycardia
  • Out-Of-Hospital Cardiac Arrest

Interventions

DEVICE

Early Extracorporeal Membrane Oxygenation (ECMO) Facilitated Resuscitation

Early use of ECMO

DEVICE

Standard Advanced Cardiac Life Support (ACLS) Resuscitation

Standard life support resuscitation

Sponsors & Collaborators

Principal Investigators

  • Demetris Yannopoulos, MD · University of Minnesota

  • Tom Aufderheide, MD · University of Minnesota

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-08-09
Primary Completion
2020-10-09
Completion
2020-10-09
FDA Device
Yes

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03880565 on ClinicalTrials.gov