Mitochondrial Methylation in Type 2 Diabetes
NCT04126551 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 27
Last updated 2024-05-07
Summary
The overarching goal of this proposal is to determine whether DNA methylation of the mitochondrial DNA impairs mitochondrial function in insulin resistant states such as overweight/obesity and type 2 diabetes.
Conditions
- Overweight
- Obesity
- Diabetes Mellitus, Type 2
- Insulin Resistance
Interventions
- OTHER
-
Methylation status
Participants will be recruited, and muscle biopsies will be obtained for methylation analyses and measuring mitochondrial function
Sponsors & Collaborators
-
University of Arizona
lead OTHER
Principal Investigators
-
Dawn K Coletta, PhD · University of Arizona
Eligibility
- Min Age
- 21 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2019-07-23
- Primary Completion
- 2023-12-31
- Completion
- 2023-12-31
Countries
- United States
Study Locations
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