Epigenetics and the Origin of Muscle Insulin Resistance in Humans
NCT01726491 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 46
Last updated 2018-01-16
Summary
The investigators are trying to understand the role of DNA (deoxyribonucleic acid) methylation in insulin resistance in skeletal muscle and blood tissues. DNA methylation is a normal chemical process in the body that modifies DNA. By studying this, the investigators hope to better understand the causes of insulin resistance.
Conditions
- Diabetes Mellitus Type 2 in Obese
- Obesity
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Lori Roust, MD · Mayo Clinic
-
Dawn K Coletta, Ph.D. · Mayo Clinic
Eligibility
- Min Age
- 21 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2012-08-31
- Primary Completion
- 2016-11-21
- Completion
- 2016-11-21
Countries
- United States
Study Locations
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