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Effect of L-arginine on Microcirculation, Myogenesis and Angiogenesis Associated With Aging, Sarcopenia and Diabetes

NCT04112875 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2019-10-02

No results posted yet for this study

Summary

This study aims was evaluated the effect of L-arginine on microcirculation, vasoreactivity / endothelial function and vascular smooth muscle of young and old women with Sarcopenia or Type 2 Diabetes Mellitus measured by Nailfold videocapillaroscopy and venous occlusion plethysmography before and after 14 days of consumption 5g oral L-arginine supplementation.

Conditions

Interventions

DIETARY_SUPPLEMENT

L-arginine

Handled powdered supplement to be mixed with water, has orange flavor for oral use.

DIETARY_SUPPLEMENT

Maltodextrin

hydrolysis of cornstarch or starch as a white powder to be mixed with water, has orange flavor for oral use.

Sponsors & Collaborators

  • Laboratory for Clinical and Experimental Research on Vascular Biology

    collaborator UNKNOWN

  • Rio de Janeiro State University

    lead OTHER

Principal Investigators

  • Daniel A Bottino, PhD · State University of Rio de Janeiro

  • Gerusa M Costa, MSc · State University of Rio de Janeiro

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
85 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-04-30
Primary Completion
2019-04-30
Completion
2019-09-30

Countries

  • Brazil

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04112875 on ClinicalTrials.gov