Capillary Glycerolemia Evolution During Physical Exercise

Summary

Maximum fatty acid oxidation is known to occur at exercise intensities between 45 and 65% VO2max and in the fasting state.

However, the optimal level may depend on various unknown factors. Glycerolemia is a good marker of the fatty acid metabolism but its evolution remains poorly described, maybe due to the difficulty of the measure.

A new device allows an easy measurement of glycerolemia during exercise and could enable personalization strategies to optimize exercise efficacy.

In this study, the investigators plan to test three different exercise types and three different fasting conditions with three replicates each to evaluate the variability of glycerolemia and its evolution during exercise.

Conditions

• Physical Activity
• Body Mass Index

Interventions

OTHER

Physical exercice - moderate intensity

standardized physical activity (moderate intensity) lasting 30 minutes and having a warm-up portion of 5 minutes

OTHER

Physical exercice - high intensity

standardized physical activity (high intensity) lasting 30 minutes and having a warm-up portion of 5 minutes

OTHER

Physical exercice - workout

standardized physical activity (bodybuilding) lasting 30 minutes and having a warm-up portion of 5 minutes

OTHER

Normal meal

\- Hyperlipidic meal Energy supply: 800 kcal Distribution of macronutrients: proteins: 15% +/- 5; carbohydrates: 40% +/- 5; lipids: 45 +/- 5 Choice of foods determined with the dietician taking into account the patient's tastes and products available on the market The same meal will be taken before the 3 sessions concerned.

OTHER

Normalized meal

\- Hyperglucidic meal Energy supply: 800 kcal Macronutrient distribution: protein 15% +/- 5; carbohydrates 60% +/- 5; lipids 25 +/- 2 Choice of foods determined with the dietician taking into account the patient's tastes and products available on the market. The same meal will be taken before the 3 sessions concerned.

OTHER

Fasting

non meal in the hour before exercise

Sponsors & Collaborators

• Assistance Publique - Hôpitaux de Paris

  lead OTHER

Principal Investigators

• Boris HANSEL, MD PHD · Assistance Publique - Hôpitaux de Paris

Study Design

Allocation

NA

Purpose

BASIC_SCIENCE

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2019-10-23

Primary Completion

2020-09-11

Completion

2020-09-11

Countries

• France

Study Locations