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Epigenetics and Periodontal Treatment

NCT02835898 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2016-07-18

No results posted yet for this study

Summary

Objective: The aim of this pilot study is to evaluate the alterations of epigenetic patterns in periodontally diseased individuals, before and after periodontal treatment, also in comparison to periodontally healthy patients.

Materials \& methods: Twenty patients were voluntarily enrolled in two groups: 10 participants with healthy periodontium, and 10 participants with chronic periodontitis. Clinical parameters were recorded and gingival biopsies were collected within the following timelines: At baseline (for both groups), after 15 days (for the diseased group only) and after two months (for the diseased group only).

Conditions

  • Periodontitis

Interventions

OTHER

Conventional periodontal treatment

Conventional routine periodontal treatment will be done for patients in test group

Sponsors & Collaborators

  • University of Milan

    lead OTHER

Principal Investigators

  • Giulio Rasperini, DDS · University of Milan

Eligibility

Min Age
26 Years
Max Age
69 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-09-30
Primary Completion
2016-06-30
Completion
2016-06-30

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02835898 on ClinicalTrials.gov