Effect of Aloe Vera Mouthwashes on the Oral Health of Children

Summary

Prevention of dental problems by controlling plaque is the best solution to maintain oral health and prevent high cost of dental treatments. Home oral care is the cornerstone in removing plaque and therefore controlling tooth decay and gum disease. Unfortunately, complete plaque removal is difficult to achieve by mechanical methods alone.

For effective plaque control antiplaque agents such as chlorhexidine mouthwash is necessary. Chlorhexidine has shown distinct advantage, but it has many side effects such as staining of the teeth and the tongue, altered taste sensation, and increased calculus formation often deters its use for long periods.

Recently the use of herbal mouthwashes is rising due to the widespread awareness that natural substances have less side effects and lower economic cost. Of various plant extracts used as a base for mouthwashes, aloe vera deserves a special attention as it has recently been introduced in dentistry after years of use in medicine field.

Many recent studies stated that aloe vera mouthwashes has shown efficiency in plaque control and prevention of gingivitis, but there is a need for more studies to determine the best protocols regarding concentration and frequency of its use. A review of the literature shows that there is no randomized controlled trials evaluating its efficiency in plaque control and prevention of gingivitis in children, which is the main purpose of this study.

Conditions

• Oral Health

Interventions

DRUG

Aloe Vera mouthwash

rinsing with aloe vera mouthwash for 5 days.

DRUG

Chlorhexidine mouthwash

rinsing with chlorhexidine mouthwash for 5 days.

DRUG

Placebo mouthwash

rinsing with placebo mouthwash for 5 days.

Sponsors & Collaborators

• Damascus University

  lead OTHER

Principal Investigators

• Doaa Adnan Alnouri, DDS, Msc Student · Department of Pediatric Dentistry, Faculty of Dental Medicine, Damascus University, Damascus, Syria

• Chaza Kouchaji, Professor · Department of Pediatric Dentistry, Faculty of Dental Medicine, Damascus University, Damascus, Syria

• Abdul Hakim Nattouf, Professor · Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Damascus University, Damascus, Syria

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

TRIPLE

Model

CROSSOVER

Eligibility

Min Age

8 Years

Max Age

12 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2019-03-01

Primary Completion

2019-06-30

Completion

2019-08-30

Countries

• Syria

Study Locations