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The Effect of Stingless Bee Honey Mouthrinse on Dental Plaque Accumulation

NCT06223243 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2024-01-25

No results posted yet for this study

Summary

Mouthrinses are recommended as a complement to mechanical methods in oral hygiene procedures to prevent and control periodontal diseases. Chlorhexidine mouthrinse has been used as a chemical plaque control agent for many years. However, in spite of its potent antimicrobial and antiplaque properties, there have been various reports of the undesirable adverse effects of chlorhexidine mouthrinse. This creates the need to look for an alternative mouthrinse that can also help in controlling plaque.

Stingless bee honey is an alternative agent which is increasingly known for its better properties and easily available compared to other types of honey. It has been reported to have many benefits for the oral cavity such as antibacterial, anti-inflammatory, and healing properties which makes it a potential therapeutic agent in periodontal therapy. However, there is a lack of clinical studies showing its efficacy in plaque control as a mouthrinse.

Hence, this study aims to investigate the ability of stingless bee honey mouthrinse to reduce plaque accumulation. This will be done through a randomised clinical trial whereby subjects will be prescribed with a mouthrinse formulation and instructed to refrain from any tooth cleaning procedure. The patient's plaque score will be recorded before and after the intervention to measure the effectiveness of the mouthrinse.

Conditions

  • Plaque Accumulation
  • Patient Acceptance

Interventions

OTHER

Stingless bee honey mouthrinse

Three bottles of 90ml of stingless bee honey of 20% concentration was given to each subject. This mouthrinse preparation was instructed for subjects to be taken 30ml each, thrice daily for three days.

OTHER

normal saline mouthrinse

Subjects were instructed to rinse with 30ml of normal saline (0.9% concentration) thrice daily for three days.

OTHER

chlorhexidine mouthrinse

Subjects were instructed to rinse with 30ml of chlorhexidine mouthrinse thrice daily for three days.

Sponsors & Collaborators

  • Universiti Sains Islam Malaysia

    lead OTHER

Principal Investigators

  • NUR AYMAN ABDUL HAYEI · FACULTY OF DENTISTRY, UNIVERSITI SAINS ISLAM MALAYSIA

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-03-01
Primary Completion
2023-09-01
Completion
2024-01-01

Countries

  • Malaysia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06223243 on ClinicalTrials.gov