MedTrace Logo

Antiplaque, Antigingivitis and Anti-inflammatory Effects of Myrrh Mouthwash

NCT04723732 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2021-01-26

No results posted yet for this study

Summary

Myrrh-based mouthwash has the potential to be a suitable alternative to the gold standard chlorhexidine mouthwash for dental plaque and gingivitis reduction. To date, however, little research has been carried out to determine its true clinical significance on periodontal health. The purpose of this study is to evaluate and compare the efficacy of 1% myrrh mouthwash with commercially available 0.2% chlorhexidine mouthwash in terms of plaque and gingivitis reduction and inflammatory mediator (interleukin-1β) inhibition.

Conditions

  • Gingivitis
  • Dental Plaque

Interventions

DRUG

Myrrh mouthwash

1% mouthwash solution of commiphora myrrha, made from Commiphora Myrrha resin extract.

DRUG

Chlorhexidine mouthwash

0.2% mouthwash solution of chlorhexidine gluconate.

DRUG

Normal saline

0.9% solution of sodium chloride, containing 9 g/L Sodium Chloride (154 mEq/L sodium and 154 mEq/L chloride)

Sponsors & Collaborators

  • King Abdulaziz University

    lead OTHER

Principal Investigators

  • Talal Zahid, M.S · King Abdulaziz University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-08-15
Primary Completion
2018-08-15
Completion
2018-12-15

Countries

  • Saudi Arabia

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04723732 on ClinicalTrials.gov