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Comparative Study of CPC+Zn Mouthwash, Dental Floss, and Essential Oils Mouthwash on Plaque and Gingivitis Reduction

NCT06607263 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2025-04-14

No results posted yet for this study

Summary

Clinical study evaluating the effectiveness of an alcohol-free mouthwash containing CPC+Zn compared to dental flossing and an essential oils-containing alcohol mouthwash in reducing dental plaque and gingivitis. This is a Phase III, single-center, double-blind trial with a parallel design. It involves 120 participants aged between 18 and 65, randomized into different groups, and spans 12 weeks.

Conditions

  • Gingival Bleeding
  • Plaque Induced Gingival Disease
  • Gingivitis and Periodontal Diseases

Interventions

DRUG

Mouthwash CPC+Zn+F

A mouthwash containing CPC + Zn and fluoride

DRUG

Essential oils mouthrinse

Essential oils mouthrinse

DEVICE

Dental floss

Dental floss

DRUG

Toothpaste

A commercially available fluoride toothpaste

DEVICE

Toothbrush

A commercially available adult toothbrush

Sponsors & Collaborators

  • Federal University of Rio Grande do Sul

    collaborator OTHER

  • Colgate Palmolive

    lead INDUSTRY

Principal Investigators

  • Cassiano K Rosing, PhD · Federal University of Rio Grande do Sul

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-09-16
Primary Completion
2024-12-09
Completion
2024-12-09

Countries

  • Brazil

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06607263 on ClinicalTrials.gov